AX-024 HCl
Product Name : AX-024 HClDescription:AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM). Inhibiting an immediate TCR signal…
PPOH
Product Name : PPOHDescription:IC50: 9 μM for the formation of arachidonate 11,12 epoxides by CYP4A2 and CYP4A3 enzymes, respectively PPOH is an inhibitor of CYP epoxidase activity on arachadonic acid.…
(S)-PFI-2 (hydrochloride)
Product Name : (S)-PFI-2 (hydrochloride)Description:(S)-PFI-2 (hydrochloride) is the inactive enantiomer of (R)-PFI-2 and may serve as a negative control. (R)-PFI-2 is a cell-permeable and potent SET7/9 inhibitor with IC50 value…
GSK-LSD1 2HCl
Product Name : GSK-LSD1 2HClDescription:GSK-LSD1 2HCl is a selective inhibitor of LSD1 with IC50 value of 16 nM . Lysine (K) -specific demethylase 1A (LSD1) is a flavin-dependent histone demethylase…
N-Benzylnaltrindole hydrochloride
Product Name : N-Benzylnaltrindole hydrochlorideDescription:Product informationCAS: 1206487-81-1Molecular Weight:541.08Formula: C33H33ClN2O3Chemical Name: (1R,2S,13R,21R)-11-benzyl-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclopentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol hydrochlorideSmiles : Cl.O12CC3=C(4OC5C6=C(C1N(CC1CC1)CC264)C=CC=5O)N(CC1C=CC=CC=1)C1=CC=CC=C13InChiKey: KDEBSUYWJUBPCB-RPQDCJIISA-NInChi : InChI=1S/C33H32N2O3.ClH/c36-26-13-12-22-16-27-33(37)17-24-23-8-4-5-9-25(23)35(19-20-6-2-1-3-7-20)29(24)31-32(33,28(22)30(26)38-31)14-15-34(27)18-21-10-11-21;/h1-9,12-13,21,27,31,36-37H,10-11,14-19H2;1H/t27-,31+,32-,33-;/m1./s1Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature…
Belizatinib
Product Name : BelizatinibDescription:Belizatinib is an oral, dual, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7 nM for wild-type recombinant ALK kinase.CAS: 1357920-84-3Molecular Weight:577.73Formula: C33H44FN5O3Chemical Name:…
Salbutamol
Product Name : SalbutamolDescription:Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).CAS: 18559-94-9Molecular Weight:239.31Formula: C13H21NO3Chemical…
BQ-123
Product Name : BQ-123Description:BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM and a Ki of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation…
HA155
Product Name : HA155Description:HA-155 is a potent and selective autotaxin (ATX) inhibitor with an IC50 of 5.7 nM.CAS: 1312201-00-5Molecular Weight:463.29Formula: C24H19BFNO5SChemical Name: {4--2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenoxy)methyl]phenyl}boronic acidSmiles : OB(O)C1C=CC(COC2C=CC(/C=C3\SC(=O)N(CC4C=CC(F)=CC=4)C\3=O)=CC=2)=CC=1InChiKey: BRWUZCBSWABPMR-XKZIYDEJSA-NInChi : InChI=1S/C24H19BFNO5S/c26-20-9-3-17(4-10-20)14-27-23(28)22(33-24(27)29)13-16-5-11-21(12-6-16)32-15-18-1-7-19(8-2-18)25(30)31/h1-13,30-31H,14-15H2/b22-13-Purity: ≥98%…
Org37684
Product Name : Org37684Description:Org37684 is a highly potent 5-HT2C receptor agonist (pEC50=8.17). Org37684 exhibits a rank order of potency of 5-HT2C>5-HT2B>5-HT2A. Its selectivity for the 5-HT2C receptor is approximately 2.5…