T Quantity UL1 TR000130, (three) National Institute on Minority Health and Well being Disparities (NIMHD) Obesity Wellness Disparities Research Center (U54MD000502; Salvy/Dutton), the Eunice Kennedy Shriver National Institute of Kid Health and Human Improvement (NICHD; R01HD092483; de la Haye/Salvy), and (four) the National Cancer Institute (NCI; 1R01CA258222, Figueiredo/Salvy/Peterson). The content is solely the duty of your authors and will not necessarily represent the official views of the National Institutes of Health. Dexcom supported this study by offering the continuous glucose monitor equipment necessary. Institutional Assessment Board Statement: The study was performed in line with the guidelines of the Declaration of Helsinki and GS-441524 Autophagy approved by the Institutional Re-view Board (or Ethics Committee) of Children’s Hospital Los Angeles (CHLA-000193, date of approval–20 December 2019). Informed Consent Statement: Written informed consent was obtained from all participants as well as a parent or guardian involved within the study including consent for publication of findings. Information Availability Statement: The datasets from this study will probably be offered from the corresponding author on written request. Conflicts of Interest: The authors declare no conflict of interest.nutrientsReviewDietary Micronutrients from Zygote to Senility: Updated Evaluation of Minerals’ Part and Orchestration in Human Nutrition all through Life Cycle with Sex DifferencesMohamed A. Farag 1,two, , Samia Hamouda 2 , Suzan Gomaa 2 , Aishat A. Agboluaje 2 , Mohamad Louai M. Hariri 2 and Shimaa Mohammad Yousof 3,four, 1Department of Pharmacognosy, College of Pharmacy, Cairo University, Cairo 11562, Egypt Division of Chemistry, College of Sciences Engineering, the American University in Cairo, New Cairo 11835, Egypt; [email protected] (S.H.); [email protected] (S.G.); [email protected] (A.A.A.); [email protected] (M.L.M.H.) Division of Medical Physiology, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah 21589, Saudi Arabia Division of Medical Physiology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt Correspondence: [email protected] (M.A.F.); [email protected] (S.M.Y.)FGIN 1-27 manufacturer Citation: Farag, M.A.; Hamouda, S.; Gomaa, S.; Agboluaje, A.A.; Hariri, M.L.M.; Yousof, S.M. Dietary Micronutrients from Zygote to Senility: Updated Review of Minerals’ Role and Orchestration in Human Nutrition throughout Life Cycle with Sex Variations. Nutrients 2021, 13, 3740. 10.3390/ nu13113740 Received: 28 September 2021 Accepted: 20 October 2021 Published: 23 OctoberAbstract: Micronutrients for instance selenium, fluoride, zinc, iron, and manganese are minerals which are essential for many body homeostatic processes supplied at low levels. The importance of these micronutrients starts early within the human life cycle and continues across its various stages. A number of studies have emphasized the essential role of a well-balanced micronutrient intake. On the other hand, the majority of research looked into or examined such problems in relation to a precise element or life stage, with the majority merely reporting the impact of either excess or deficiency. Herein, within this assessment, we will look in depth at the orchestration in the principal element needs across the human life cycle beginning from fertility and pregnancy, passing by means of infancy, childhood, adolescence, and reaching adulthood and senility, with insight around the interactions amongst them and underlying action.