ORL1 antagonist 1

Product Name : ORL1 antagonist 1Description:ORL1 antagonist 1 is an opioid receptor-like 1 (ORL1) antagonist with an IC50 of 61 nM.CAS: 1174985-59-1Molecular Weight:367.88Formula: C20H22ClN5Chemical Name: N-{methyl}cyclopentanamineSmiles : CC1=C(C2C=NC=CC=2)N(N=C1CNC1CCCC1)C1=NC=CC=C1ClInChiKey: GZENXSQONSXYLR-UHFFFAOYSA-NInChi :…

THZ531

Product Name : THZ531Description:THZ531 is a selective and covalent inhibitor of both CDK12 and CDK13 with IC50s of 158 nM and 69 nM, respectively.CAS: 1702809-17-3Molecular Weight:558.07Formula: C30H32ClN7O2Chemical Name: (2E)-N-{4-amino}piperidine-1-carbonyl]phenyl}-4-(dimethylamino)but-2-enamideSmiles :…

Zidebactam

Product Name : ZidebactamDescription:Zidebactam (WCK-5107) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL.CAS: 1436861-97-0Molecular Weight:391.40Formula: C13H21N5O7SChemical Name: formohydrazido}carbonyl)-1,6-diazabicyclooctan-6-yl]oxidanesulfonic acidSmiles…

(S)-Mapracorat

Product Name : (S)-MapracoratDescription:(S)-Mapracorat is a selective and less active glucocorticoid receptor agonist.CAS: 887375-15-7Molecular Weight:462.48Formula: C25H26F4N2O2Chemical Name: (2S)-4-(5-fluoro-2,3-dihydro-1-benzofuran-7-yl)-4-methyl-1--2-(trifluoromethyl)pentan-2-olSmiles : CC(C)(C(O)(CNC1C=CC=C2N=C(C)C=CC=12)C(F)(F)F)C1C=C(F)C=C2CCOC2=1InChiKey: VJGFOYBQOIPQFY-DEOSSOPVSA-NInChi : InChI=1S/C25H26F4N2O2/c1-15-7-8-18-20(5-4-6-21(18)31-15)30-14-24(32,25(27,28)29)13-23(2,3)19-12-17(26)11-16-9-10-33-22(16)19/h4-8,11-12,30,32H,9-10,13-14H2,1-3H3/t24-/m0/s1Purity: ≥98% (or refer to the Certificate of…

Bisdemethoxycurcumin

Product Name : BisdemethoxycurcuminDescription:Bisdemethoxycurcumin is a natural inhibitor of NF-kappaB, MMP-2, and MMP--9 pathways. Bisdemethoxycurcumin suppresses migration and invasion of human cervical cancer HeLa cells.CAS: 33171-05-0Molecular Weight:308.33Formula: C19H16O4Chemical Name: (1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dioneSmiles…

Methylprednisolone

Product Name : MethylprednisoloneDescription:Acremine F is a fungal metabolite that has been found in Acremonium.CAS: 83-43-2Molecular Weight:374.47Formula: C22H30O5Chemical Name: (1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopentaphenanthren-7-oneSmiles : C1C2((O)C3(C)2CC3(O)C(=O)CO)2(C)C=CC(=O)C=C21InChiKey: VHRSUDSXCMQTMA-PJHHCJLFSA-NInChi : InChI=1S/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1Purity: ≥98% (or refer to the…